Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/3686
Title: Development of electrochemical sensors for the determination of certain pharmaceuticals
Researcher: Augustine, Pearl
Guide(s): Girish Kumar, K
Keywords: Electrochemical Sensors
Pharmaceuticals
Trimethoprim
Ketoconazole
Lamivudine
Domperidone
Nimesulide
Drugs
Upload Date: 24-Apr-2012
University: Cochin University of Science and Technology
Completed Date: 28/06/2008
Abstract: The quality of a drug is determined after establishing its authenticity by testing its purity and quality of the pure substance in the drug and its formulations.Ion selective sensors have become one of the most effective and powerful means for analytical scientists in the determination of drug substances and are playing an increasing role in pharmaceutical analysis.ISEs are cost effective,easy to prepare and can be rapidly manipulated . Potentiometric ion selective sensors have been developed for six drugs namely trimethoprim, ketoconazole, lamivudine, domperidon, nimesulide and Lomefloxacin. The sensors fabricated include both PVC membrane sensor as well as carbon paste sensor. A total of sixteen different sensors have been developed. The response parameters of all the sensors have been studied and the sensors were applied to the determination of the drugs in pharmaceutical formulations and also in real samples like urine.
Pagination: xvii, 251p.
URI: http://hdl.handle.net/10603/3686
Appears in Departments:Department of Applied Chemistry

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01_title.pdfAttached File20.89 kBAdobe PDFView/Open
02_certificate.pdf21.68 kBAdobe PDFView/Open
03_declaration.pdf13.95 kBAdobe PDFView/Open
04_acknowledgements.pdf55.94 kBAdobe PDFView/Open
05_preface.pdf62.18 kBAdobe PDFView/Open
06_contents.pdf116.53 kBAdobe PDFView/Open
07_list of tables.pdf49.04 kBAdobe PDFView/Open
08_list of figures.pdf57.18 kBAdobe PDFView/Open
09_chapter 1.pdf790.4 kBAdobe PDFView/Open
10_chapter 2.pdf348.01 kBAdobe PDFView/Open
11_chapter 3.pdf299.41 kBAdobe PDFView/Open
12_chapter 4.pdf402.37 kBAdobe PDFView/Open
13_chapter 5.pdf498.05 kBAdobe PDFView/Open
14_chapter 6.pdf354.68 kBAdobe PDFView/Open
15_chapter 7.pdf471.46 kBAdobe PDFView/Open
16_chapter 8.pdf385.22 kBAdobe PDFView/Open
17_chapter 9.pdf44.78 kBAdobe PDFView/Open
18_references.pdf421.04 kBAdobe PDFView/Open
19_list of publications.pdf122.35 kBAdobe PDFView/Open


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