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Title: Wolbachia surface protein wsp induced immune responses in patients With human lymphatic filariasis
Researcher: Shiny, C
Guide(s): Narayanan, R B
Keywords: Filarial Genome
Wucheraria bancrofti Brugia malayi and Brugia timori
Upload Date: 27-Nov-2014
University: Anna University
Completed Date: 01/06/2009
Abstract: Lymphatic filariasis is a mosquito borne parasitic disease caused newlineby thread like filaroid nematode worms that include Wucheraria bancrofti newlineBrugia malayi and Brugia timori They lodge in the lymphatic system a newlinenetwork of nodes and vessels that maintain the body s fluid balance and an newlineessential component of body s immune system Lymphatic filariasis also newlineknown as Elephantiasis puts at risk more than a billion people across the newlineglobe As part of the Filarial Genome Project many novel genes that are newlineinvolved in immune evasion and parasite survival mechanisms have been newlineidentified from various stages of the parasite life cycle Immune responses newlineand clinical manifestations that are observed in the endemic population newlinedepends to a great extent on various factors from the parasite that modulate or newlineregulate host immune system The consensus of opinion among workers in newlinethis field is that prolonged parasite survival in the host reflects its ability to newlinesuppress or modulate host immune responses This phenomenon and the newlineresulting pathogenesis assumes a broader perspective when parasite newlineassociation with its enodosymbiont Wolbachia bacteria is considered Hence newlinehuman lymphatic filariasis has been described as a disease caused by both newlinenematode and the bacterial components This necessitates a closer look at the newlinerole of Wolbachia component in filarial pathogenesis newline newline
Pagination: xxxi, 251p.
Appears in Departments:Faculty of Science and Humanities

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01_title.pdfAttached File39.07 kBAdobe PDFView/Open
02_certificate.pdf7.31 kBAdobe PDFView/Open
03_abstract.pdf21.99 kBAdobe PDFView/Open
04_acknowledgement.pdf7.32 kBAdobe PDFView/Open
05_content.pdf73.09 kBAdobe PDFView/Open
06_chapter1.pdf1.6 MBAdobe PDFView/Open
07_chapter2.pdf202.03 kBAdobe PDFView/Open
08_chapter3.pdf24 MBAdobe PDFView/Open
09_chapter4.pdf164.28 kBAdobe PDFView/Open
10_appendix.pdf140.09 kBAdobe PDFView/Open
11_reference.pdf246.59 kBAdobe PDFView/Open
12_publication.pdf8.02 kBAdobe PDFView/Open
13_vitae.pdf5.52 kBAdobe PDFView/Open

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