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Title: Characterization And Emulsifying Activities Of A Quorum Sensing Biosurfactant Produced By A Marine Bacterium
Researcher: K. Abraham Peele
Guide(s): Vidya Prabhakar Kodali, Bharath Kumar Ravuru
University: Vignans Foundation for Science Technology and Research
Completed Date: 2017
Abstract: newlineOur understanding about the ecology of hydrocarbon (oil) degrading microorganisms newlinewhich are mostly bacteria, fungi have greatly enhanced in recent periods. newlineBiosurfactants and bioemulsifers are the amphiphilic compounds that are produced newlineextracellular or as a part of the cell membrane by bacteria. Hydrosphere consists of newlinemarine ecological environment which is more prone to oil pollution by contamination. newlineUnderstanding how microorganisms degrade hydrocarbons, and thereby mitigate newlineecosystem damage is important to target the problem and to plan the strategy. newlineBiosurfactants produced by biofilm-producing bacteria has a profound impact in newlinemedical biotechnology, food production, pharmaceutical, bioremediation and newlinehydrometallurgy. Biofilms are the bacterial communities that are regulated by many newlinesignaling processes. Biofilms have the exopolysaccharide (EPS) sheath which protects newlinethe cells of the bacteria from various adverse conditions. The typical newlineExoPolysaccharide formed from the biofilm bacteria has the maximum carbohydrate newlineportion and considered to be the main ingredient in the biofilm. Research suggests that newlineamount of EPS produced by different bacteria possess different concentration and newlinecomposition. Generally, the kind of bacteria which produces Exopolymeric materials newlinesuch as biosurfactant, has the role in antibiotic resistance, as it offers many regulatory newlinepathways to act against antibiotics. Natural plant extracts which contains several newlinephenolic compounds have great role in pharmaceutical field. Due to the safety issues newlineconcerned with the natural extracts which could be a characteristic feature to become newlinea drug, our present work deals with the screening antibiofilm agents using natural newlineextracts and disturbing the quorum sensing signal which is responsible for the newlineformation of the biofilm. Garlic offered a promising approach in the field of quorum newlinesensing signal blocking mechanism. newline
Pagination: 136
Appears in Departments:Department of Biotechnology

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