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Title: Studies on genetic and molecular aspects of scribble knockdown induced tumor progression mitochondrial dysfunction and its alleviation by Isatin derivatives in Drosophila cancer model
Researcher: Yadav Amarish Kumar
Guide(s): Srikrishna Saripella
Keywords: Life Sciences,Biology and Biochemistry,Biochemistry and Molecular Biology
University: Banaras Hindu University
Completed Date: 2017
Abstract: The term Cancer is derived from a Greek word Karkinos by a physician Hippocrates around 460-370 B.C for carcinoma-tumors. Cancer has a very old history as evidenced by the presence of bone-cancer in mummies and a recorded case of breast cancer from the ancient Egypt in 1500 B.C (Sudhakar, 2009; Faguet, 2015). Cancer is a complex genetic disease, which can affect nearly every organ/system in the human body and one of the leading causes of human-mortality globally. World Health Organization (WHO) has estimated around 11 million deaths from cancer worldwide by 2030 (Stefenatos et al., 2011). In general, cancer can be defined as uncontrolled cell-proliferation leading to growth of mass of cells, called tumor/lumps. Sustained cell-proliferation and evading apoptotic-signals are the characteristic hallmarks of growing tumor (Hanahan et a.l, 2011). Tumor can be classified in two classes as benign and malignant (Idikio, 2011). newline
Appears in Departments:Department of Biochemistry

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