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Researcher: Sati Priyanka
Guide(s): Anita Pandey and Anju Rani
University: Graphic Era University
Completed Date: 23-01-2017
Abstract: Recent upsurge in the therapeutic potential of medicinal plants as a source of newlinephytochemicals is gaining momentum all over the globe. Among other issues of research, newlinescreening of medicinal plants for active constituents and evaluating the biological activity deserve newlinepriority attention in view the increasing demand of herbal medicine in different systems of newlinemedicine. Ginkgo biloba leaves contain pharmaceutically important flavonoid glycosides and newlineginkgolides which improve blood flow, act as antioxidants and also used as memory enhancers and newlineanti-vertigo agents. While Ginkgo has been well recognized for medicinally important active newlineingredients, the species has received limited attention for its antimicrobial properties. Keeping this newlinebackground in view, Ginkgo plants were selected for detailed investigations for nutritional and newlinephytochemicals constituents, standardization of methodology for extraction and quantification of newlineactive ingredients and antimicrobial activity present in the leaf extracts of Ginkgo biloba growing newlinein the Indian Himalayan Region. newlineFive trees, located in Almora and Nainital districts of Uttarakhand, were selected for the newlinecollection of leaf material in different seasons (i.e. spring, rainy and autumn). These five trees were newlinegenetically different. Extraction of active ingredients from powdered leaf samples was performed newlinein 5 solvent systems (3 pure solvents i.e., methanol, ethyl acetate, n-Butanol), combination of newlineacetone/water (3:2) - 1 set and aqueous (1 set). The nutritional and phytochemical values could be newlineassessed for different biochemical parameters including proximate, trace elements, total phenolic, newlineflavonoid contents and antioxidant activity using spectrophotometric methods. Quantification of newlineGinkgo leaf flavonoid glycosides was conducted using HPLC following standard procedure along newlinewith different extraction techniques. Optimization of time and temperature for detection of newlineginkgolides and bilobalide was performed by TLC method. Factorial analysis was performed to correlate the influence
Appears in Departments:Deptt. of Biotechnology

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01_title.pdf.pdfAttached File150.68 kBAdobe PDFView/Open
02_certificates.pdf.pdf313.86 kBAdobe PDFView/Open
03_acknowledgements.pdf.pdf17.48 kBAdobe PDFView/Open
04_contents.pdf.pdf96.21 kBAdobe PDFView/Open
05_preface.pdf.pdf27.24 kBAdobe PDFView/Open
06_list of tables figures plates and abbreviations.pdf.pdf38.11 kBAdobe PDFView/Open
07_chapter1.pdf.pdf237.53 kBAdobe PDFView/Open
08_chapter2.pdf.pdf215.88 kBAdobe PDFView/Open
09_chapter3.pdf.pdf1.63 MBAdobe PDFView/Open
10_chapter4.pdf.pdf456.22 kBAdobe PDFView/Open
11_chapter5.pdf.pdf792.78 kBAdobe PDFView/Open
12_chapter6.pdf.pdf25.04 kBAdobe PDFView/Open
13_references.pdf.pdf340.29 kBAdobe PDFView/Open

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