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Title: Bioengineered skin constructs derived from human mesenchymal stem cells for wound healing
Researcher: Dinesh M.G.
Guide(s): Mangathayaru K.
Keywords: A bracteolate
A indica
Gingival Mesenchymal Stem cells
Hystem HP scaffold
Skin constructs
Wound healing
University: Sri Ramachandra University
Completed Date: 03/07/2018
Abstract: The present study was therefore aimed to evaluate the wound healing effect of methanolic extract of Acalypha indica and Aristolochia bracteolata by using different in the vitro cell culture system The study involves cellular proliferation migration anti inflammation and associated mechanism of action for the scientific support as also evaluation of the unique characteristics of Gingival MSCs on induction with plant extracts for a demonstration of their potential to secrete cytokines and growth factors that could be of therapeutic and immune modulatory importance Characterization of the function of commonly secreted proteins and genes involved in wound healing and other metabolic disorders by qPCR and western blotting studies shall supplement the work objective to ascertain the role of plant extracts Based on these results the work proposes to develop Bio engineered tissue constructs encapsulated with stem cells that could be evaluated for supportive effect towards developing a wound healing graft tissue newline
Pagination: 1-148
Appears in Departments:College of Biomedical Sciences

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acknowledgement.pdfAttached File141.9 kBAdobe PDFView/Open
annexures.pdf625.23 kBAdobe PDFView/Open
bibliography.pdf517.64 kBAdobe PDFView/Open
certificate.jpg96.23 kBJPEGThumbnail
chapter-1 introduction.pdf498.69 kBAdobe PDFView/Open
chapter-2 review of literature.pdf963.33 kBAdobe PDFView/Open
chapter-3 aim & objective.pdf304.88 kBAdobe PDFView/Open
chapter-4 methodology.pdf651.88 kBAdobe PDFView/Open
chapter-5 results.pdf5.18 MBAdobe PDFView/Open
chapter-6 discussion.pdf317.04 kBAdobe PDFView/Open
chapter-7 conclusion.pdf272.37 kBAdobe PDFView/Open
chapter-8 salient observations.pdf279.65 kBAdobe PDFView/Open
declaration.jpg48.05 kBJPEGThumbnail
list of content.pdf194.81 kBAdobe PDFView/Open
list of figures.pdf151.73 kBAdobe PDFView/Open
list of tables.pdf85.17 kBAdobe PDFView/Open
title page.pdf105.18 kBAdobe PDFView/Open

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