Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/19245
Full metadata record
DC FieldValueLanguage
dc.coverage.spatialChemistryen_US
dc.date.accessioned2014-06-12T12:05:38Z-
dc.date.available2014-06-12T12:05:38Z-
dc.date.issued2014-06-12-
dc.identifier.urihttp://hdl.handle.net/10603/19245-
dc.description.abstractThe present study is focussed on the stereoselective total synthesis of some naturally occurring lactones, semiplenamides and isolation of bioactive natural products. newline6-Substituted-5,6-dihydro-2H-pyran-2-one is an important structural subunit in many biologically promising natural products. newline(6 S)-5,6-Dihydro-6-[(2 R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one and dodoneine are amongst them that attracted our focus for newlinesynthesis due to their interesting biological activities and structural similarities. The pyranone unit of both molecules was brought newlinethrough a common intermediate with varying asymmetric centres. These lactone intermediates, ( S) - and ( R)-2-(6-oxo-3, 6-dihydro-2H-pyran-2-yl) acetaldehydes have further been accomplished from 1,3- newlinepropanediol employing Maruoka asymmetric allylation and ring closing metathesis reaction. These intermediates were converted into desired natural products (6 S)-5,6-Dihydro-6-[(2 R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one and dodoneine through Grignard newlinereaction.en_US
dc.format.extent194 p.en_US
dc.languageEnglishen_US
dc.relation-en_US
dc.rightsuniversityen_US
dc.titleTotal Synthesis of naturally occurring lactones and Semiplenamides C and E and Investigation on Novel Diterpenoids of Jatropha Multifidaen_US
dc.title.alternative-en_US
dc.creator.researcherShashikanth Ben_US
dc.subject.keywordJatrophaen_US
dc.subject.keywordlactonesen_US
dc.subject.keywordMultifidaen_US
dc.subject.keywordSemiplenamidesen_US
dc.subject.keywordSynthesisen_US
dc.description.noteReferences included in the chaptersen_US
dc.contributor.guideDas, Biswanathen_US
dc.publisher.placeKukatpallyen_US
dc.publisher.universityJawaharlal Nehru Technological University, Hyderabaden_US
dc.publisher.institutionFaculty of Chemistryen_US
dc.date.registeredn.d.en_US
dc.date.completed2013en_US
dc.date.awardedn.d.en_US
dc.format.dimensions-en_US
dc.format.accompanyingmaterialNoneen_US
dc.type.degreePh.D.en_US
dc.source.inflibnetINFLIBNETen_US
Appears in Departments:Department of Chemistry

Files in This Item:
File Description SizeFormat 
01_title.pdfAttached File181.33 kBAdobe PDFView/Open
02_dedication.pdf152.53 kBAdobe PDFView/Open
03_declaration.pdf61.65 kBAdobe PDFView/Open
04_certificate.pdf133.88 kBAdobe PDFView/Open
05_acknowledgment.pdf133.1 kBAdobe PDFView/Open
06_remarks & abbreviations.pdf103.99 kBAdobe PDFView/Open
07_contents.pdf94.16 kBAdobe PDFView/Open
08_abstract.pdf92.38 kBAdobe PDFView/Open
09_chapter 1.pdf306.01 kBAdobe PDFView/Open
10_chapter 2.pdf4.88 MBAdobe PDFView/Open
11_chapter 3.pdf915.6 kBAdobe PDFView/Open
12_chapter 4.pdf2.99 MBAdobe PDFView/Open
13_chapter 5.pdf5.58 MBAdobe PDFView/Open
14_list of publications.pdf117.05 kBAdobe PDFView/Open


Items in Shodhganga are protected by copyright, with all rights reserved, unless otherwise indicated.

Altmetric Badge: