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Title: Condensation of 2-Methyl Quinazolines, 2-mercapto-3H-Quinazoline acid hydrazides respectively with aromatic Aldehydes active halo compounds and Carbonyl Compounds
Researcher: Bireddy, Srinivasa Reddy
Guide(s): Dubey, P K
Naidu, A
Keywords: Compounds
Upload Date: 6-Jun-2014
University: Jawaharlal Nehru Technological University, Hyderabad
Completed Date: 2013
Abstract: CONDENSATION OF 2-METHYLQUINAZOLINONES, 2-MERCAPTO-3H- QUINAZOLIN-4-ONES AND QUINAZOLINONE ACID HYDRAZIDES RESPECTIVELY WITH AROMATIC ALDEHYDES, ACTIVE HALO COMPOUNDS AND CARBONYL COMPOUNDS newline Keeping in view the importance of uinazolinones ring systems, the newlinepresent thesis describes the synthesis and characterization of several quinazolinones based intermediates which may later on find application as potentially biologically active molecules or intermediates for the synthesis of more complicated derivatives. This thesis consists of five chapters: newlineCHAPTER 1: This Chapter deals with the introduction to malaria and quinazolinones - their importance, nomenclature, physical, chemical properties and synthesis. CHAPTER 2: This chapter describes the synthesis and characterization of newlinenew compounds like N-substituted-2-styrylquinazolinones. The synthesis newlinehas been studied under two sets of conditions, namely, (i) Conventional conditions and (ii) Green conditions. newlineChapter 3: This Chapter is divided into three sections: namely, Section-A, newlineSeciton-B and Section-C respectively. newlineSection-A: This Section describes the reaction of 2-mercapto-3H-quinazolin- newline4-one with chloroacetic acid and subsequent chemical reactions of the intermediary products. Section-B: This Section describe the condensation of 2-mercapto-3H- newlinequinazolin-4-one with phenacyl bromide and subsequent chemical reactions of the intermediary products.
Pagination: 192 p.
Appears in Departments:Department of Chemistry

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01_title.pdfAttached File128.44 kBAdobe PDFView/Open
02_dedication.pdf134.06 kBAdobe PDFView/Open
03_declaration.pdf172.07 kBAdobe PDFView/Open
04_certificate.pdf248.93 kBAdobe PDFView/Open
05_acknowledgement.pdf160.13 kBAdobe PDFView/Open
06_contents.pdf209.21 kBAdobe PDFView/Open
07_abstract.pdf155.07 kBAdobe PDFView/Open
08_chapter 1.pdf543.11 kBAdobe PDFView/Open
09_chapter 2.pdf854.91 kBAdobe PDFView/Open
10_chapter 3.pdf525.21 kBAdobe PDFView/Open
11_chapter 4.pdf562.3 kBAdobe PDFView/Open
12_chapter 5.pdf430.96 kBAdobe PDFView/Open
13_biblography.pdf213.45 kBAdobe PDFView/Open
14_publications.pdf206.86 kBAdobe PDFView/Open

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