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Researcher: Joshi Swati
Guide(s): Dr. Navin Kumar and Dr. Nishant Rai
University: Graphic Era University
Completed Date: 24-10-2016
Abstract: newline Plants have been practiced as therapeutics since the beginning of human civilization. Plant extracts have several advantages over the purified compounds or synthesized molecules e.g. extracts are relatively cheaper, easily available and have better efficacy due to the synergistic interplay of different components. Uttarakhand is a treasure of medicinal plants. Elaeocarpous sphaericus (common name: Rudraksha) is famous for its spiritual and ethnopharmacological significance. Different studies have demonstrated various medicinal properties of the extracts of leaf, fruit and bead of E. sphaericus except anticancer properties. Pinus wallichiana (common name: Blue pine/Kail) is popular for its timber quality, gum and resin, but very limited reports are available on its pharmacological properties. The present study is focused to prepare a extract from the leaves of E. sphaericus and needles of P. wallichiana, using a modern method of extraction (i.e. pressurized liquid extraction), and to analyze its phytochemical and bio-medicinal properties. newlineThe plant parts were collected from Dehradun and Uttarkashi districts of Uttarakhand. Aqueous and methanolic extracts of the leaves of two plants were prepared through PLE in the accelerated solvent extractor (ASE). newlinePhytochemical analyses of the extracts were performed by various conventional (spectrophotometeric) and modern methods (HPTLC and GC-MS). Preliminary qualitative analysis of both the plant extracts revealed the presence of carbohydrate, proteins, phenols and flavonoids in aqueous and methanolic extracts. Total phenolic and total flavonoid contents were found higher in the extracts of E. sphaericus than that of P. wallichiana extracts. HPTLC analysis of E. sphaericus leaf extracts showed the presence of ascorbic acid, quercetin, gallic acid and hesperidin, whereas P. wallichiana needle extract showed the presence of ascorbic acid and quercetin. GC-MS analyses revealed the presensce of 9-12-octadecadien-1-ol (linoleyl alcohol), stigmost-5-En-3-ol, pentadeca
Appears in Departments:Deptt. of Biotechnology

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013_chpater7.pdf.pdf148.39 kBAdobe PDFView/Open
014_references.pdf.pdf314.25 kBAdobe PDFView/Open
01_title.pdf.pdf213.66 kBAdobe PDFView/Open
02_certificates.pdf.pdf137.51 kBAdobe PDFView/Open
03_acknowledgements.pdf.pdf86.33 kBAdobe PDFView/Open
04_contents.pdf.pdf356.29 kBAdobe PDFView/Open
05_preface.pdf.pdf213.15 kBAdobe PDFView/Open
06_list of tables and figures.pdf.pdf207.64 kBAdobe PDFView/Open
07_chapte1.pdf.pdf156.93 kBAdobe PDFView/Open
08_chapter 2.pdf.pdf1.11 MBAdobe PDFView/Open
09_chapter 3.pdf.pdf161.73 kBAdobe PDFView/Open

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