Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/13579
Title: Synthesis and characterization of novel heterocyclic compounds
Researcher: Jain, Payal
Guide(s): Mohd. Yusuf
Keywords: Chemistry
Heterocyclic Chemistry
Upload Date: 3-Dec-2013
University: Punjabi University
Completed Date: 2012
Abstract: Synthesis of heterocyclic compounds is an important part of the synthetic organic chemistry that constitutes a considerable part of the modern researches that are occurring presently throughout the world. Heterocycles also play an important role in the design and discovery of new physiologically and pharmacologically active compounds. The five membered heterocyclics bearing two and three hetero atoms (O, N and S) are found to be highly significant due to their immense biological applications. Thus, in this thesis the investigations have been focused upon the syntheses of new bisthiadiazolines, bisthiazolidinones, bispyrazolines and bischromones. Chapter-I contains many observations from the literature regarding the various types of heterocyclic compounds. Major emphasis has been laid down upon the synthesis and pharmaceutical significance of the five and six membered heterocyclic products. Chapter-II has been divided into three parts IIa, IIb and IIc which describe the synthesis of bisthiadiazolines and bisthiazolidinones. Here the bisthiosemicarbazones built around the alkyl chains of varying lengths undergo cyclization reactions with acetic anhydride and ethyl bromoacetate. Chapter-III which is also subdivided into three parts IIIa, IIIb and IIIc contains the chemical transformation of various bischalcones to yield bispyrazolines built around the varying length aliphatic chains. In chapter IIIa, 1,3,5-triphenyl-bispyrazolines linked via 3-aryl ring have been synthesized while the chapter IIIb describes the synthesis of 1,3-diphenyl-5-thienyl bispyrazolines. The chapter IIIc deals with the synthesis of 1,3,5-triphenyl-bispyrazolines linked via 5-aryl ring. The last chapter IV describes the synthesis of bischromones linked via 2-aryl ring with the varying length alkyl chains. These bisheterocyclics has been prepared from the cyclization reactions of bischalcones with iodine in the presence of DMSO.
Pagination: 307p.
URI: http://hdl.handle.net/10603/13579
Appears in Departments:Department of Chemistry

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01_title.pdfAttached File12.59 kBAdobe PDFView/Open
02_certificate.pdf23.62 kBAdobe PDFView/Open
03_declaration.pdf10.22 kBAdobe PDFView/Open
04_acknowledgements.pdf23.22 kBAdobe PDFView/Open
05_preface.pdf13.93 kBAdobe PDFView/Open
06_contents.pdf8.39 kBAdobe PDFView/Open
07_general consideration.pdf15.45 kBAdobe PDFView/Open
08_chapter 1.pdf148.48 kBAdobe PDFView/Open
09_chapter 2.pdf1.32 MBAdobe PDFView/Open
10_chapter 3.pdf1.94 MBAdobe PDFView/Open
11_chapter 4.pdf324.79 kBAdobe PDFView/Open
12_summary.pdf25.27 MBAdobe PDFView/Open
13_abstrat.pdf8.52 kBAdobe PDFView/Open


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