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Title: Longitudinal assessment of optic nerve head progression in glaucoma
Researcher: Ramesh S Ve
Guide(s): Ronnie George
Keywords: Longitudinal assessment of optic nerve head progression in glaucoma
University: Birla Institute of Technology and Science
Completed Date: 
Abstract: Aim: To determine the structural changes using Scanning Laser Ophthalmoscope newline(Heidelberg Retinal Tomography: HRT III), Optical Coherence Tomography (Stratus OCT), newlineScanning Laser Tomography (GDx VCC) and functional damage estimated with Humphrey newlineVisual Field (HVF (24-2) SITA Standard) and Frequency Doubling Perimetry (FDP) - on a newlinepopulation based cohort of subjects with primary glaucoma and ocular hypertension (OHT). newlineMethods: Detailed periodic clinical examination of subjects with primary glaucoma, OHT newlineand an age matched control group was done over a 5 year follow up. Subjects underwent bi newlineannual follow-up and controls had annual visit. Humphrey visual field examination (HVF newline24-2, SITA Std), GDX, HRT and OCT was performed during every visits. Functional newlineprogression on HVF was determined using the point wise linear regression (Progressor) newlineanalysis. The clinical data obtained from the optic nerve head imaging tools (HRT, GDx and newlineOCT) were considered, progression or change analysis was obtained from all instruments. newlineSubjects were classified into two groups progressed or non progressed based on functional newlineloss on HVF and FDP. newlineMain outcome of this study is to investigate the efficacy of Stereo ONH photography, GDx, newlineOCT and HRT in detecting progression of glaucoma and their relationship with functional newlineloss as assessed by HVF and FDP in a subset of population based cohort with Glaucoma, at newlinerisk and controls. newlineResults: A total of 54 eyes of 30 subjects with primary glaucoma (open angle 16 (53.3%) newlineand angle closure 14 (46.7%)), 54 eyes of 28 OHT subjects and 18 eyes of 10 age matched. newline
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Appears in Departments:Humanities & Social Sciences

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