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Title: Synthesis characterization and biological evaluation of 1 3 4 oxadiazoles 1 2 4 triazoles and 1 3 4 thiadiazoles containing fatty acid moiety as pendant
Researcher: Jubie , S
Guide(s): Dhanabal, S P
Keywords: Spirulina platensis, Stearic acid, Antidepressant, Estimation of dopamine antimicrobial
University: JSS University
Completed Date: 26/04/2014
Abstract: Stearic acid, a saturated fatty acid was isolated from the microalga Spirulina platensis. Some novel stearic newlineacid analogues having 1,3,4-oxadiazole, 1,2,4-triazole and 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole are newlinesynthesized and characterized by IR, NMR and mass spectral analysis. All the synthesized compounds newlinewere screened for antimicrobial activity by using cup plate method. The synthesized compounds have newlinebeen further screened for their antidepressant activity in swiss albino mice by forced swim test (FST), newlinemidbrain dopamine has been estimated and quantified. All the compounds showed good antimicrobial activity and compound 6 showed significant antidepressant activity.
Pagination: i-xx, 1-99,i-xi
Appears in Departments:College of Pharmacy

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01_title.pdf.pdfAttached File151.04 kBAdobe PDFView/Open
02_certificates.pdf.pdf782.52 kBAdobe PDFView/Open
03_acknowledgements.pdf.pdf56.36 kBAdobe PDFView/Open
04_contents.pdf.pdf8.18 kBAdobe PDFView/Open
05_list of figures.pdf.pdf29.29 kBAdobe PDFView/Open
06_list of tables.pdf.pdf11.59 kBAdobe PDFView/Open
07_chapter- 01.pdf333.89 kBAdobe PDFView/Open
08_chapter- 02.pdf388.89 kBAdobe PDFView/Open
09_chapter- 03.pdf157.31 kBAdobe PDFView/Open
10_chapter-04.pdf709.03 kBAdobe PDFView/Open
11_chapter 05.pdf2.56 MBAdobe PDFView/Open
12_chapter 06.pdf123.23 kBAdobe PDFView/Open
13_refereneces.pdf191.58 kBAdobe PDFView/Open

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