Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/11163
Title: Antilithiatic Effect of TribulusTerrestris
Researcher: Aggarwal, Anshu
Guide(s): Tandon, Chanderdeep
Keywords: Antilithiatic
Hyperoxaluria
Tribulus Terrestris
Upload Date: 13-Sep-2013
University: Jaypee University of Information Technology, Solan
Completed Date: 04/04/2012
Abstract: Urolithiasis is the third most common disorder of the urinary tract affecting 2 20% population worldwide. Urinary calculi are caused by various etiological factors with a worldwide increasing incidence and prevalence causing substantial morbidity and economic burden. Archaeological findings give profound evidence that humans have suffered from kidney stones for centuries. Epidemiological data have shown that calcareous stones are found in a majority of kidney stones majorly composed of calcium oxalate and calcium phosphate. Calcium oxalate stones are found in two different varieties, calcium oxalate monohydrate or Whewellite, and calcium oxalate dihydrate or Weddellite. Calcium oxalate monohydrate, the thermodynamically most stable form, is observed more frequently in clinical stones than calcium oxalate dihydrate and it has a greater affinity for renal tubular cells, thus responsible for the formation of stones in kidney. The formation of such concretion encompasses several physiochemical events beginning with crystal nucleation, growth, aggregation and ending by retention within urinary tract. The mechanisms governing the induction of all these processes remain speculative. Surgical operation, lithotripsy and local calculus disruption using high-power laser are widely used to remove calculi along with dietary interventions and therapies like thiazide diuretics and alkali-citrate to prevent recurrence but scientific evidence for their efficacy is less convincing.
Pagination: 
URI: http://hdl.handle.net/10603/11163
Appears in Departments:Department of Biotechnology

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01_title.pdfAttached File82.97 kBAdobe PDFView/Open
02_certificate.pdf70.17 kBAdobe PDFView/Open
03_acknowledgement.pdf243.26 kBAdobe PDFView/Open
04_contents.pdf167.34 kBAdobe PDFView/Open
05_list of tables figures.pdf444.72 kBAdobe PDFView/Open
06_chapter 1.pdf1.08 MBAdobe PDFView/Open
07_chapter 2.pdf4.87 MBAdobe PDFView/Open
08_chapter 3.pdf2.61 MBAdobe PDFView/Open
09_chapter 4.pdf5.64 MBAdobe PDFView/Open
10_chapter 5.pdf2.76 MBAdobe PDFView/Open
11_summary & conclusion.pdf805.53 kBAdobe PDFView/Open
12_list of publications.pdf199.76 kBAdobe PDFView/Open
13_bibliography.pdf3.21 MBAdobe PDFView/Open


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