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Title: Purification and Characterization of a Novel Antilithiatic Protein from the Seeds of Dolichos Biflorus and its Validation in Rat Urolithiatic Model
Researcher: Bijarnia, Rakesh Kumar
Guide(s): Tandon, Chanderdeep
Keywords: Dolichos Biflorus
Upload Date: 11-Sep-2013
University: Jaypee University of Information Technology, Solan
Completed Date: 19/11/2008
Abstract: Stone formation in the kidney is one of the oldest and most wide spread diseases known to man. Kidney stone formation also called as urolithiasis is a common chronic disorder affecting 10-15% of the general population world wide. Advancement in various treatments of urolithiasis has tried to sort out the problem to some extent, but recurrence and persistent side effects after the treatment restrict their use. An alternate, using phytotherapy which is advantageous, safe and culturally acceptable is being sought. Many medicinal plants have been employed since ages to treat urinary stones. The rationale behind their use is not well established through systematic and pharmacological studies, except for some composite herbal drugs and plants. The discovery and elucidation of the mechanism of action, in particular the clinical role of these herbal remedies can make an important contribution to treatment of urinary stone disease as an alternative or adjunct therapy. Till date, various plant extracts have been studied to reduce the incidence of urolithiasis but the identification of naturally occurring calcium oxalate inhibitory biomolecules from plants was hampered in the past by limitations in identification method.
Appears in Departments:Department of Biotechnology

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01_title.pdfAttached File81.38 kBAdobe PDFView/Open
02_certificate.pdf103.2 kBAdobe PDFView/Open
03_acknowledgement.pdf295.19 kBAdobe PDFView/Open
04_contents.pdf159 kBAdobe PDFView/Open
05_list of tables figures.pdf768.68 kBAdobe PDFView/Open
06_chapter 1.pdf6.09 MBAdobe PDFView/Open
07_chapter 2.pdf4.72 MBAdobe PDFView/Open
08_chapter 3.pdf10.02 MBAdobe PDFView/Open
09_chapter 4.pdf1.97 MBAdobe PDFView/Open
10_summary & conclusion.pdf551.09 kBAdobe PDFView/Open
11_list of publications.pdf130.59 kBAdobe PDFView/Open
12_bibliography.pdf2.02 MBAdobe PDFView/Open

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