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Title: Rapid Genotypic and mutational analysis of clinical HBV isolates in North Indian Population
Researcher: Tuteja Amit
Guide(s): Navkiran Kaur
Keywords: Hepatits
Genomic Signatures
Amity University
University: Amity University
Completed Date: 2015
Abstract: Present study is designed with an aim to develop a method based on comparative genomics and bioinformatics analysis of the characteristics of HBV genome, which is based on extraction of HBV genotype-specific Genomic Signatures (GS). These GS can be used as a tool for identification of new markers for efficient and early diagnosis of HBV genotypes on an oligonucleotide based chip. Whole genome profiling using oligonucleotide based approach will enable not only genotype identification, but also delineation of mixed and recombinant types. newlineThe study is also aimed to understand the whole-genome profile of the circulating HBV isolates in a subset of north Indian population, to identify novel mutations if any in the study population and to correlate mutation profile with disease severity. newline
Appears in Departments:Amity Institute of Biotechnology

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1. introduction.pdfAttached File99.43 kBAdobe PDFView/Open
2. review of literature .pdf1.64 MBAdobe PDFView/Open
3. objectives .pdf28.75 kBAdobe PDFView/Open
4. material and methods .pdf1.67 MBAdobe PDFView/Open
5. results .pdf2.08 MBAdobe PDFView/Open
6. discussion .pdf156.77 kBAdobe PDFView/Open
7. conclusion .pdf53.76 kBAdobe PDFView/Open
8. references.pdf161.5 kBAdobe PDFView/Open
9. appendices .pdf749.2 kBAdobe PDFView/Open
certificate.pdf101.02 kBAdobe PDFView/Open
preliminary pages.pdf187.46 kBAdobe PDFView/Open
title.pdf64.26 kBAdobe PDFView/Open

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